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Although to penetrate into the intimate mysteries of nature and thence to learn the true causes of phenomena is not allowed to us, nevertheless it can happen that a certain fictive hypothesis may suffice for explaining many phenomena.
-Leonhard Euler
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Although To Penetrate Into The Intimate Mysteries

Leonhard Euler
Although to penetrate into the intimate mysteries of nature and thence to learn the true causes of phenomena is not allowed to us, nevertheless it can happen that a certain fictive hypothesis may suffice for explaining many phenomena.
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Science May Statistics

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[coining phrase "null hypothesis"] in relation to any experiment we may speak of this hypothesis as the "null hypothesis," and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis.
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Mr. darwin's hypothesis is not, so far as i am aware, inconsistent with any known biological fact; on the contrary, if admitted, the facts of development, of comparative anatomy, of geographical distribution, and of palaeontology, become connected together, and exhibit a meaning such as they never possessed before; and i, for one, am fully convinced that if not precisely true, that hypothesis is as near an approximation to the truth as, for example, the copernican hypothesis was to the true theory of the planetary motions.
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Every mind has its particular standard of good and bad, and of right and wrong. this standard is made by what one has experienced through life, by what one has seen or heard; it also depends upon one's belief in a certain religion, one's birth in a certain nation and origin in a certain race. but what can really be called good or bad, right or wrong, is what comforts the mind and what causes it discomfort. it is not true, although it appears so, that it is discomfort that causes wrongdoing. in reality, it is wrongdoing which causes discomfort, and it is right-doing which gives comfort.
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In real science a hypothesis can never be proved true...a science which confines itself to correlating phenomena can never learn anything about the reality underlying the phenomena, while a science which goes further than this and introduces hypotheses about reality, can never acquire certain knowledge of a positive kind about reality; in whatever way we proceed, this is forever denied us.
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Tormented by conflicting feelings, i appealed to reason ; and it is reason which, amid so many dogmatic contradictions, now forces the hypothesis upon me. a priori dogmatism, applying itself to god, has proved fruitless: who knows whither the hypothesis, in its turn, will lead us? i will explain therefore how, studying in the silence of my heart, and far from every human consideration, the mystery of social revolutions, god, the great unknown, has become for me an hypothesis, i mean a necessary dialectical tool.
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