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All that belongs to human understanding, in this deep ignorance and obscurity, is to be sceptical, or at least cautious, and not to admit of any hypothesis whatever, much less of any which is supported by no appearance of probability.
-David Hume
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All That Belongs To Human Understanding, In

David Hume
All that belongs to human understanding, in this deep ignorance and obscurity, is to be sceptical, or at least cautious, and not to admit of any hypothesis whatever, much less of any which is supported by no appearance of probability.
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Ignorance Understanding Obscurity

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[coining phrase "null hypothesis"] in relation to any experiment we may speak of this hypothesis as the "null hypothesis," and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis.
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Tormented by conflicting feelings, i appealed to reason ; and it is reason which, amid so many dogmatic contradictions, now forces the hypothesis upon me. a priori dogmatism, applying itself to god, has proved fruitless: who knows whither the hypothesis, in its turn, will lead us? i will explain therefore how, studying in the silence of my heart, and far from every human consideration, the mystery of social revolutions, god, the great unknown, has become for me an hypothesis, i mean a necessary dialectical tool.
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It has been pointed out already that no knowledge of probabilities, less in degree than certainty, helps us to know what conclusions are true, and that there is no direct relation between the truth of a proposition and its probability. probability begins and ends with probability.
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Mr. darwin's hypothesis is not, so far as i am aware, inconsistent with any known biological fact; on the contrary, if admitted, the facts of development, of comparative anatomy, of geographical distribution, and of palaeontology, become connected together, and exhibit a meaning such as they never possessed before; and i, for one, am fully convinced that if not precisely true, that hypothesis is as near an approximation to the truth as, for example, the copernican hypothesis was to the true theory of the planetary motions.
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