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When a liver becomes cirrhotic, those are the common complications. we see that the patients have bleeding from their stomach and intestines. they have abdomens that become full of fluid. their ankles swell with the same type of fluid, and they also can become confused and not themselves. those are kind of the main things that we see when people get end-stage liver disease and have cirrhosis.

-John Roberts

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When A Liver Becomes Cirrhotic, Those Are

John Roberts

When a liver becomes cirrhotic, those are the common complications. we see that the patients have bleeding from their stomach and intestines. they have abdomens that become full of fluid. their ankles swell with the same type of fluid, and they also can become confused and not themselves. those are kind of the main things that we see when people get end-stage liver disease and have cirrhosis.

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    <p style="font-size: 1.2rem; font-style: italic; margin-bottom: 10px;">"when a liver becomes cirrhotic, those are the common complications. we see that the patients have bleeding from their stomach and intestines. they have abdomens that become full of fluid. their ankles swell with the same type of fluid, and they also can become confused and not themselves. those are kind of the main things that we see when people get end-stage liver disease and have cirrhosis."</p>
    <footer style="font-size: 1rem; font-weight: bold;">— John Roberts</footer>
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Confused People Ankles

More From John Roberts

End-stage liver disease refers to a liver that's failing, and a very high percentage of those livers are what we call cirrhotic, or the patient's liver has become cirrhotic, and what cirrhosis is, is the scarring of the liver tissue.

There are many different causes of the scarring. viruses are common. hepatitis b, hepatitis c, what we call autoimmune diseases where the body attacks the liver itself such as primary biliary cirrhosis is an autoimmune disease; sclerosing cholangitis is an autoimmune disease; and so those diseases where the liver is being destroyed by either the virus or an autoimmune disease, it can only scar, and why it doesn't regenerate has to do with the fact that there is this ongoing scar tissue that blocks that regeneration.

When we think about living donor transplant, what we're banking on is the ability of the liver to regenerate itself. now, it's not the same sort of regeneration we think about with the starfish where we cut off the arm and it grows a new arm. with the liver, what happens is the remaining liver gets bigger, and your body knows the size of the liver that it needs, and when it recognizes that there is not enough liver, it sends nutrients and signals to the liver and says "get bigger."

Pretty much everybody knows there are not enough organs for all of those patients who need to get transplants, and what happens is, is that organs are actually directed in liver transplantation to those patients who are the sickest. so the patients who have the greatest chance of dying in the next three months or so are the ones who get the priority for the liver transplant.

If men were equally at risk from this condition - if they knew their bellies might swell as if they were suffering from end-stage cirrhosis, that they would have to go nearly a year without a stiff drink, a cigarette, or even an aspirin, that they would be subject to fainting spells and unable to fight their way onto commuter trains - then i am sure that pregnancy would be classified as a sexually transmitted disease and abortions would be no more controversial than emergency appendectomies.

Operating-room errors hold a special terror for patients, if only because they seem like the most avoidable kind of complications. the occasional horror stories of patients who have the wrong leg removed or the wrong knee replaced generate the most headlines, as do tales of patients whose identities are mixed up entirely.

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